Pain reliever, nasal decongestant, antihistamine. Multi-Symptom: Contains 3 medicines: Acetaminophen - headache. Phenylephrine HCl - sinus pressure; nasal congestion. Chlorpheniramine maleate - runny nose/sneezing; itchy, watery eyes. Multi-Symptom Night: Contains 3 medicines: Acetaminophen - headache. Phenylephrine HCl - sinus pressure; nasal congestion. Diphenhydramine HCl - runny nose/sneezing; itchy, watery eyes.