Pain reliever/fever reducer, nasal decongestant, cough suppressant, antihistamine (Antihistamine in nighttime only). Day (non-drowsy) Contains 3 Medicines: fever/headache - acetaminophen; sore throat - acetaminophen; nasal congestion - phenylephrine HCl; coughing - dextromethorphan HBr. Night contains 4 medicines: fever/headache - acetaminophen; sore throat - acetaminophen; nasal congestion - phenylephrine HCl; coughing - dextromethorphan HBr; runny nose - chlorpheniramine maleate.