Lowers Cholesterol. Centrum Cardio is the first and only (among leading brands) complete daily multivitamin with CoroWise phytosterols - Significantly lowers LDL (bad) cholesterol; Cholesterol-lowering benefits of Phytosterols may be seen in as early as 4 weeks. May reduce the risk of heart disease. Just one Centrum Cardio multivitamin taken twice daily provides the complete nutrition you'd expect from Centrum, along with an ingredient that lowers cholesterol. (Foods or dietary supplements containing at least 400 mg per serving of free phytosterols taken twice a day with meals for a daily total intake of at least 800 mg, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. A daily serving of Centrum Cardio (2 tablets) contains 800 mg of CoroWise phytosterols) A daily serving of Centrum Cardio (2 tablets) contains 800 mg of CoroWise, a natural ingredient derived from soybeans that works by blocking cholesterol absorption. Made in USA.