Pain Reliever/Fever Reducer, Nasal Decongestant, Cough Suppressant, Antihistamine (in Nighttime only). Day (Non-Drowsy) Contains 3 Medicines: Fever/Headache, Sore throat - Acetaminophen; Nasal congestion - Phenylephrine HCl; Coughing - Dextromethorphan HBr. Night Contains 4 Medicines: Fever/Headache, Sore throat - Acetaminophen; Nasal congestion - Phenylephrine HCl; Coughing - Dextromethorphan HBr; Runny nose - Chlorpheniramine Maleate.